Momo's offers services from bereavement groups to suicide awareness training.
The cafe was forced to close a few months back when their building became unusable following constant flooding.
Now with a new base in their sights they need to raise £3,000 for a deposit on the new home.
Owner Claire Rigby says the cafe is needed in St Helens to give that extra support to those who need it: "There's just been this massive outcry in the town of people going 'we need to bring Momo's back, we're missing it, my mental health is defying.
"I'm getting phone calls, I'm getting inbox's saying 'we need Momo's back'"
Some of the services which the cafe offer are bereavement drop in groups, breastfeeding support and suicide awareness training among many other kinds of support which is asked for by those in the town.
Claire has many plans moving forward some of which include helping disabled people into work and offering them the chance to train users on customer services, catering and independent living through work placements and experience.
There's plans to become a training centre for those with learning difficulties which is also in the works: "We want to breakdown the barriers so people with learning difficulties have a really good quality of life."
To donate visit the cafe's fundraising page.